Thank you for your reply, Kate.

Firstly, may I correct you. Ehlers Danlos Syndrome is not an autoimmune condition, it is a heritable disorder of connective tissue.

Secondly, I'm not sure what you mean about sliding and gliding. Any movement that involves sustained muscle control, even gentle isometric exercise, leads to prolonged muscle contractions. I am very severely affected, I cannot stand unaided, I struggle to walk more than a few metres and even gentle tai chi exercises flare up my symptoms to the point where I can no longer care for myself.