Below is an interesting study that is a double blind RCT and has been peproduced with the same results.
What the full article shows is that in the management of low back pain the manipulation and physiotherapy (non-manip) are better then placebo and gp treatment. Furthermore more that placebo is in fact better than GP treatment.
Most studies continue to fail to document and or test perhaps what is the differential we are looking for. Is it quality of life, stress, pain? Who knows. What I agree with is that we are totally crap at studying what we need to to support our profession. I can only blame the under graduate research tutors and supervisors for this as the under grads look to their guidance both in under grad programs, masterd and PHD's. It really bugs the ---- out of me and many others!
Koes BW, Bouter LM, van Mameren H, Essers AH, Verstegen GM, Hofhuizen DM, Houben JP, Knipschild PG
Title: Randomised clinical trial of manipulative therapy and physiotherapy for persistent back and neck complaints: results of one year follow up
Source: BMJ 1992 Mar 7;304(6827):601-605
CONCLUSIONS: Manipulative therapy and physiotherapy are better than general practitioner and placebo treatment.