The polio virus attacks and destroys motor anterior horn cells in the cord. The central nervous system adapts to these deficits through neuroplastic changes often through budding of axons. The results are that fewer intact nerves supply greater numbers of motor fibres which enhances function and muscle force generation. However later in life with many of the usual changes with aging, Polio sufferers have appeared to experience a relapse of similar symptoms, especailly specific increase in weakness of previously affected muscles and general fatigue. It is now generally believed that this is not a resurgence of the virus but an effect of what is almost an overuse of the neural conduction over years. The general advice is preservation strategies for these individuals. Strengthening exercise are not advised, as the current understanding is that this could hassen functional deterioration. Therefore activity pacing, use of aids etc to prolong function is the general advice. It is unknown if a similar phenomenum will show itself with other conditions as increasing sufferers age. There are many self-support group websites around