hiya!

Clinically there is moderate evidence to prove that Buccal GTN is more effective at controlling exertional angina chest pain due to its longer acting duration. There is not an overwhelming collection of evidence about different drug delivery systems and whether one is more effective than the other. However it is possible to state that BGTN and SLGTN are equally effective at relieving acute coronary chest pain/angina. Yet BGTN is proven to be more effective over a longer period of time than single dose SLGTN.

It also has less side effects like headache. And Increases a patients exertional tolerance due to its delivery system.


CRESCENDO ANGINA
Many people have angina that can come on with exercise but is well controlled with drugs. This is known as stable angina. Unstable (or crescendo) angina is defined as episodes of angina on minimal effort or at rest. It can occur when you get angina for the first time, or when your angina has recently worsened. If you get severe chest pain at rest, which comes on suddenly, and reoccurs even after you have used nitrate tablets or spray

Gender differences:
Premenopausal women have a lower risk of angina than men, probably due to the favourable effect of natural oestrogen on the blood lipid profile. After menopause this advantage is lost and the female risk of CAD and symptoms rapidly approaches that of men of similar age.

jess