You also have to consider that this simply needs more time. If he has had significant muscle damage, which it sounds like he has he may need anywhere up to another 4 weeks. Is the oedema firm (pitting) or loose, as any pitting oedema can take a long time to clear. As long as he is getting no worse there may be nothing to worry about. However, I am not saying forget about looking at pathology like DVT, simply that I have seen similar injuries that can appear severe at 4 weeks but just need more time and Rx.
The two distinct lumps can be little intramuscular or subcutaneous blood clots and difficulty walking due to resticted calf flexibility. Try heel raises etc...
If it is myositis, which it probably isnt if he's been resting and hasn't been getting rubbed, then NSAIDS like he's using, and especially Indocid, i think, which has been shown to inhibit calcification too, may be useful. And rest of course.
But I'm not suggesting you don't follow up other pathology if you suspect it. :rolleyes :rolleyes