Re ‘painfree signalling’. I’ve always had the notion that the nervous system can predict what our conscious reaction to it’s signals might be, and perhaps it has the means to alter it’s signalling methods, in the interests of recovery, to avert what might be deemed as possible adverse reactions. Given a circumstance where the nerve is ‘aware’ that a painful signal might cause, for instance, a panic reaction which could lead to further injury, can the nerve generate a ‘painfree’ signal and thus avert such a reaction whilst initiating a local response at the same time.
Mosley at his finest:
TEDxAdelaide - Lorimer Moseley - Why Things Hurt - YouTube