Not professional experience, but 11 yrs with a close other person. A good GP is essential, preferably one up to date with stem-cell and T-cell research. The ME/CFS society (there is one in each state of Aust) can help with management. The worst thing is exercise. The only logocal approach is carefully graded walking, start with 50 m, then a day or two later, 70 m-100 m. As a routine.
Sleep when required, stay awake when able.