Hey guys, I am trying to find some answers and maybe some help for my brother. He has been battling something along these same lines for a couple years now (longer if you count first signs of weakness). I am not a doctor nor do I know what the test results are etc when he went to the doctor, so I am going to tell you some of the observatins I have made and maybe someone can help us out. My brother is 21 and has been complaining of reduced hand strength since he was 17 or 18, like some of you he first started noticing a lack of grip strength when squeezing or shaking hands. He now has lost much of his muscle tissue and seems to hold his hands with his index fingers constantly pulled in toward the palm. He has definetly been slowed by this in terms of movements in the fingers and arms. Not only are both of his hands affected but also his legs. He has trouble walking and seems to not be able to lift his feet more than a few inches off the ground and slides them when he walks. The way he walks seems to be something he has to constantly think about, for example it seems that he is thinking to himself the whole time, "lift leg, move leg forward, put leg down". Its a jerky process at best, I noticed that none of you guys have said anything about your walking but I was wondering if anyone else has any of these troubles. Please understand my frustrations and provide any help or info you think might help. We have been to Duke and UVA and received no answers, so if you can suggest doctors or anything like that I will greatly appreciate that too. I will thank you in advance as I am sure all of you know the frustrations he is going through.